Vascular Calcification

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منابع مشابه

[Vascular calcification in CKD].

As doenças cardiovasculares (DCV) constituem a principal causa de mortalidade em pacientes com doença renal crônica (DRC).1 O risco de óbito por DCV nessa população chega a ser 10 a 30 vezes maior que aquele observado na população geral. Esse aumento da mortalidade também ocorre em pacientes nos estágios precoces da DRC,2 assim como naqueles submetidos a transplante renal.3 A alta prevalência d...

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Magnesium Counteracts Vascular Calcification

Cardiovascular disease is the leading cause of mortality in patients with chronic kidney disease (CKD). Cardiovascular events are 5 to 30× more likely to occur in end-stage renal disease (ESRD) patients compared with the general population of the same age, sex, and race. In dialysis patients, arterial stiffness has been identified as an independent risk factor for cardiovascular mortality. An i...

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Vascular calcification mechanisms.

Vascular calcification is highly correlated with cardiovascular disease mortality, especially in patients with ESRD or diabetes. In addition to the devastating effects of inappropriate biomineralization seen in cardiac valvulopathies, calciphylaxis, and idiopathic arterial calcification, vascular calcification is now recognized as a marker of atherosclerotic plaque burden as well as a major con...

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Genetics of vascular calcification.

Recessive mutations in the NTE5 gene were recently described in lower-extremity vascular calcification. ENPP1 mutations were previously described in a severe disorder of vascular calcification in infancy. Together these data support that extracellular adenosine and pyrophosphate are essential components of the pathways in vascular disease. Arterial calcification by impairing blood flow and redu...

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Mechanism of vascular calcification

In the early 1900s, cholesterol deposition in atherosclerosis was considered a passive, degenerative, inevitable and end-stage process of ageing. After decades of research, it is now recognized as an active, regulated, treatable and preventable disorder related to deposition and oxidation of lipoprotein components. Similarly, in the past few decades, vascular calcification also has been conside...

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ژورنال

عنوان ژورنال: Chinese Medical Journal

سال: 2017

ISSN: 0366-6999

DOI: 10.4103/0366-6999.204931